.VMS File Extension

NanoZoomer Virtual Microscope Specimen

Developer Hamamatsu
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What is a VMS file?

A VMS file is a slide specimen image created by Hamamatsu NanoZoomer, a pathology slide scanning device. It is a compressed archive that contains an index file, two or more .JPEG images, and an optimization file. VMS files can be viewed using the slide-viewing software that comes with NanoZoomer or in other slide-viewing applications.

More Information

Digital slide scanners and virtual microscopes save slide specimen images in a variety of image formats. Hamamatsu NanoZoomer saves slide images in the VMS, .VMU, and .NDPI formats. The VMS format packages a single slide image as at least two JPEGs. One JPEG contains a high-resolution copy of the slide, and the other contains a lower-resolution copy. If the high-resolution image would be larger than 65,535 pixels on one side, NanoZoomer instead saves the high-resolution image as multiple JPEGs, which slide-viewing software automatically combines into one image.

In addition to JPEG files, VMS files contain plain text index and optimization files. These files contain metadata that slide-viewing applications use to show slide images correctly.

How to open a VMS file

Windows users can open VMS files in Aperio Technologies ImageScope, OpenSlide, ImageJ, or NetScope Viewer. Mac and Linux users can open VMS files in OpenSlide or ImageJ.

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Programs that open VMS files

Mac
Free
Linux
Free

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